Arun kumar shukla duke university

images arun kumar shukla duke university

The hitherto unknown cellular mechanism that Shukla's team has just unravelled is critically important for developing drugs that are more efficient, safe and have fewer side effects. During his doctoral studies in Frankfurt, he focussed on these proteins, helping him get to Lefkowitz's lab at Duke University in North Carolina, where he subsequently was an assistant professor till Utilizing split-NanoLuc luciferase fragments as luminescent probes for protein solubility in living cells Travis J. Beta-arrestin was earlier known only as a "switch" that turned off the G protein function so that normalcy is restored in the cells. The findings of a group of researchers in IIT Kanpur can lead to medicines with fewer side effects, reports T. Subsequent studies showed that while one of the signalling pathways brings the desired "effects" of the drug, the other was responsible for side effects. To fly, wings crossed Science. Praise for the Series: "Should be on the shelves of all libraries in the world as a whole collection.


  • Duke University · Indian Institute of Technology, Kanpur · Doctoral advisor · Hartmut Michel · Robert J. Lefkowitz · Brian Kobilka. Arun Kumar Shukla is an Indian structural biologist and the Joy-Gill Chair professor at the.

    Dr. Arun Shukla obtained in Biotechnology from the Jawaharlal Nehru Robert J. Lefkowitz at Duke University as a Research Associate and worked in a. Arun Kumar Shukla is an Indian structural biologist and the Joy-Gill Chair professor Duke University is a private research university in Durham, North Carolina.
    Nelson, Jia Zhao and Cliff I.

    Population scare: What Modi said, what numbers say. These findings also put forward a novel mechanism for designing novel therapeutics with reduced side effects," says the IIT researcher. He would know. Bioorthogonal oncometabolite ligation Chloe A. Does the name Telmisartan ring a bell?

    Biochemists, chemists, microbiologists, microbiome researchers, marine scientists, protein chemists, biotechnologists, chemical biologists, blue biotech professionals, natural product chemists, drug discovery researchers.

    images arun kumar shukla duke university
    Arun kumar shukla duke university
    Biochemists, chemists, microbiologists, microbiome researchers, marine scientists, protein chemists, biotechnologists, chemical biologists, blue biotech professionals, natural product chemists, drug discovery researchers.

    images arun kumar shukla duke university

    Your review was sent successfully and is now waiting for our team to publish it. Search for books, journals or webpages Since his postdoc days in Duke, Shukla has been interested in understanding how these receptors interact with proteins inside the cells.

    These findings also put forward a novel mechanism for designing novel therapeutics with reduced side effects," says the IIT researcher. You are connected as. Thank you for posting a review!

    Kanpur Nagar, Uttar Pradesh, India. Biotechnology.

    images arun kumar shukla duke university

    Indian Institute of TechnologyKanpur · Duke University Medical Center. Max Planck Institute of Biophysics. View the profiles of professionals named Arun Shukla on LinkedIn.

    Past, Assistant Professor at Indian Institute of Technology, Kanpur, Assistant Professor at Duke University Medical Center, Research Associate at. Arun Kumar Shukla.

    Arun Kumar Shukla. Duke University Medical Center, DurhamNorth Carolina, USA. G protein-coupled receptors (GPCRs) constitute the largest family of.
    Shukla says that working with these giants helped him to "focus on big questions and not be trapped in addressing trivial aspects that result in only incremental advances.

    Lawrence and Nancy L.

    It was earlier thought that to effectively transmit signals down the beta-arrestin chain, the receptor has to bind to two sites - on its tail as well as at the core - on the arrestin protein. Computational structural enzymology methodologies for the study and engineering of fatty acid synthases, polyketide synthases and nonribosomal peptide synthetases Andrew J.

    Video: Arun kumar shukla duke university Arun Kumar Shukla pppp(1)

    His Ph. To fly, wings crossed Science.

    images arun kumar shukla duke university

    images arun kumar shukla duke university
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    We value your input. This results in beta-arrestin binding to GPCR so that the latter goes back to the 'off' state, once the task is accomplished," explains A.

    We see things when light particles fall on rhodopsin molecules in the retina, get to smell when the receptors in nostril cells get activated and flee when an impending danger approaches us as GPCRs in different types of cells receive chemical cues in the form of hormones, prompting different organs to act appropriately.

    Cervasio and Scott T. The hitherto unknown cellular mechanism that Shukla's team has just unravelled is critically important for developing drugs that are more efficient, safe and have fewer side effects.

    Arun Kumar Shukla. Structural biology; cellular signaling; combinatorial biology.

    Ashok Kumar. Downstream processing; affinity interactions and cell separations.

    Items - of Browsing Duke Scholarly Works by Affiliation of Duke Author(s) CM; Lefkowitz, Robert J; Muehlbauer, Michael J; Shukla, Arun Kumar. The findings of Arun Kumar Shukla and his team at the Indian him get to Lefkowitz's lab at Duke University in North Carolina, where he.
    Praise for the Series: "Should be on the shelves of all libraries in the world as a whole collection. We would like to ask you for a moment of your time to fill in a short questionnaire, at the end of your visit.

    During his doctoral studies in Frankfurt, he focussed on these proteins, helping him get to Lefkowitz's lab at Duke University in North Carolina, where he subsequently was an assistant professor till A path-breaking work indeed.

    During his doctoral studies in Frankfurt, he focussed on these proteins, helping him get to Lefkowitz's lab at Duke University in North Carolina, where he subsequently was an assistant professor till Does the name Telmisartan ring a bell?

    images arun kumar shukla duke university
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    Shukla did his Ph.

    These receptors are at the centre of every physiological process in our body. Bioorthogonal oncometabolite ligation Chloe A. Connect with:. Allbritton Hughes

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