Therapeutically, HR-OCT helps confirm tumor regression by allowing for direct tumor measurement on the scans and comparison of serial pictures. It has also been used intraoperatively as an adjunct to surgery, as described below. Conjunctival papilloma: Features and outcomes based on age at initial examination. Diffuse and poorly defined lesions should also raise concern for a malignant process such as sebaceous carcinoma pagetoid spread. She was successfully managed with a seventh surgical excision and intraoperative application of MMC 0. The use of postoperative topical mitomycin C in the treatment of recurrent conjunctival papilloma. Nevertheless, carcinoma rarely develops from dysplastic conjunctival papilloma [ 264 ]. Detection of human papillomavirus DNA on the fingers of patients with genital warts. In pediatric patients, maternal HPV exposure should be elicited.
Specifically, conjunctival papillomas are benign squamous. An inflammatory response may cause a benign lesion to increase in size.
Video: Conjunctival papilloma causes of blood subconjunctival hemorrhage
. This procedure allows for precise tissue excision with minimal blood loss and trauma.
Papilloma Causes, symptoms, and treatment
Clinical profiles, treatment, outcome, and factors related to recurrence were The most common location of conjunctival papilloma was the caruncle (43%). allows for precise tissue excision with less blood loss and trauma to tissue.
Kaliki et al evaluated the clinical features, treatment, and outcomes in patients with conjunctival papilloma based on age at initial examination.
This makes topical IFN attractive in the pediatric population and those with any ocular surface issues. Availability of data and materials Not applicable.
Instead, a combinational approach for recurrent and resistant papillomas has been reported in many studies [ 53919495 ].
HR-OCT shows a well-defined dome-shaped elevation of hyperreflective epithelium. Clin Exp Ophthalmol. It is hard to identify the free margin and depth of conjunctiva papilloma during excision surgery because of conjunctival bleeding and lack of microscopic analysis. Given that conjunctival papilloma is relatively rare, the majority of data is from reports and series, and no head-to-head comparisons between treatment approaches are yet available for this challenging condition.
Update on Diagnosis and Management of Conjunctival Papilloma Eye and Vision Full Text
Conjunctival Papilloma Treatment & Management This procedure allows for precise tissue excision with minimal blood loss and trauma to.
Papillomas are benign lumps that might cause problems in some locations but do not spread to others. When found and removed early, they.
Since then, studies have found intraoperative MMC to be effective even in very extensive lesions [ 50].
Verweij J, Pinedo HM. Ultra high-resolution anterior segment optical coherence tomography in the diagnosis and management of ocular surface squamous neoplasia.
Clinical features differentiating benign from malignant conjunctival tumors in children. Natural history of genital warts: Analysis of the placebo arm of 2 randomized phase III trials of a quadrivalent human papillomavirus types 6, 11, 16, and 18 vaccine.
Conjunctival papilloma is a benign epithelial tumor of the conjunctiva that can occur at any age in pediatric and adult patients.
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|HR-OCT is a non-invasive diagnostic tool that can help identify lesions without the need for biopsy and assess treatment response.
As anterior segment imaging evolved with improved image quality, easier operation, and expanded applications, non-invasive imaging diagnosis and surveillance have become a reality and increasingly valuable in the management of ocular surface tumors.
The recurrence of conjunctival papilloma is not uncommon, especially for those patients underwent surgical excision alone. Furthermore, no studies exist on its specific use for conjunctival papilloma. Conjunctival forceps and blunt scissors are typically used for excision while care is taken not to touch the tumor with the surgical instruments.